| Title： | Expert Consensus on the Diagnosis and Treatment of Vibrio Vulnificus Sepsis (2024) |
| Edition： | Updated |
| Classification： | Experts consensus |
| Field： | Diagnosis and Treatment |
| Countries and regions： | China |
| Guidelines users： | clinical doctor |
| Evidence classification method： | Level of evidence: Level I (high quality): Further research is unlikely to alter our confidence in the results of clinical efficacy assessments. Grade II (moderate-certainty): further research may alter our confidence in the results of the efficacy assessment. Grade III (low quality): further research is likely to alter our confidence in the results of the assessment of efficacy, and is highly likely to alter the results. Grade IV (very low quality): any efficacy assessment is uncertain. The unsupported recommendation category is formed by expert clinical experience, and the evidence category is defined as a good practice statement (GPS). This consensus uses the recommendations of the modified Delphi method to reach consensus and a questionnaire is distributed to experts in emergency medicine and related specialties. Each recommendation needs to be upvoted by at least 80% of the experts. |
| Development unit： | Emergency Department of The First Affiliated Hospital of Wenzhou Medical University；Emergency physicians branch of Chinese Medical Association |
| Registration time: | 2024-07-22 |
| Registration number： | PREPARE-2024CN035 |
| Purpose of the guideline: | Vibrio vulnificus sepsis is an acute and severe disease caused by Vibrio vulnificus infection, which is more common in coastal areas in China, and once it develops into Vibrio vulnificus necrotizing soft tissue infection (Vv-NSTIs), the mortality rate is as high as 50%, and the surviving patients not only need to face high medical costs, but also have more sequelae and lower quality of life. In September 2023, the United States Centers for Disease Control and Prevention published an article in JAMA magazine warning that the issue of Vibrio vulnificus infection has attracted public attention. Vibrio vulnificus sepsis has the characteristics of acute onset, violent progression, and difficult treatment, and requires rapid diagnostic evaluation and emergency treatment. The release of the "Diagnosis and Treatment Protocol for Vibrio vulnificus Sepsis (2018)" has played an important role in guiding emergency doctors to evaluate, diagnose and treat Vibrio vulnificus sepsis in a scientific and standardized manner, and has significantly reduced the mortality rate of patients. With the continuous progress of academic theories and techniques in emergency medicine, further research has been carried out on the pathogenesis, etiological examination, and prognosis prediction of Vibrio vulnificus sepsis. In particular, the promulgation of the Expert Consensus on the Clinical Diagnosis and Treatment of Necrotizing Soft Tissue Infections provides new guidance for the core problem of Vv-NSTIs. At the same time, we have also made new progress in the construction and management of the emergency process of Vibrio vulnificus sepsis, which is necessary to update the original plan. The Emergency Physician Branch of the Chinese Medical Doctor Association, the Emergency Medicine Branch of the Chinese Medical Association, the Emergency Resuscitation and Disaster Medicine Professional Committee of the Chinese Medical Doctor Association and other organizations have established a compilation committee, combined with the latest progress and clinical diagnosis and treatment experience at home and abroad, and after repeated discussions and correspondence review revisions, this consensus is formulated in order to have better guidance and operability for clinical practice and reduce the mortality and disability rates of Vibrio vulnificus sepsis. |
Latest registration
