| 标题： | 急性虫螨腈中毒临床诊治急诊专家共识 |
| title： | Expert consensus on diagnosis and treatment of acute Chlorfenapyr poisoning |
| 版本： | 原创版 |
| version： | Original |
| 分类： | 专家共识 |
| classification： | Experts consensus |
| 领域： | 诊疗 |
| field： | Diagnosis and Treatment |
| 国家和地区： | 中国 |
| Country and region： | China |
| 指南使用者： | 急诊科 |
| Guide users： | Emergency Department |
| 证据分级方法： | 推荐等级分为三级。A（强）：将来的研究几乎不可能改变当前的评估结果。B（中）：将来的研究可能对目前的评估结果有重要影响, 从而可能改变当前推荐。C（弱）：将来的研究很可能对目前的评估结果有重要影响, 从而很可能改变当前推荐。 |
| Evidence grading method： | The recommendation level is divided into three levels. A (strong): it is almost impossible for future research to change the current evaluation results. B (middle): future research may have an important impact on the current evaluation results, which may change the current recommendation. C (weak): future research is likely to have an important impact on the current evaluation results, which is likely to change the current recommendation. |
| 制定单位： | 温州医科大学附属第一医院 |
| Formulating unit： | Emergency Department of The First Affiliated Hospital of Wenzhou Medical University |
| 注册时间： | 2024-07-01 |
| Registration time： | |
| 注册编号： | PREPARE-2024CN916 |
| Registration number： | |
| 指南制订的目的： | 虫螨腈是一种广谱杀虫农药，急性中毒机制主要是干扰呼吸链，阻碍了二磷酸腺苷( ADP) 生成三磷酸腺苷( ATP) 的偶联，急性虫螨腈中毒尚无特效专用解，毒剂和拮抗剂。近年来，国内虫螨腈中毒的发病率呈逐年上升趋势，病死率极高，并且无相应的有效救治手段。人们对急性虫螨腈中毒认识不足，缺乏有效的救治手段。目前我国对于虫螨腈中毒救治尚无相应的指南或共识，为提高急性虫螨腈中毒救治成功率，拟制定本推荐意见以指导临床实践。 |
| Purpose of the guideline： | Chlorfenapyr is a broad-spectrum insecticidal pesticide, and its acute poisoning mechanism mainly interferes with the respiratory chain, hindering the coupling of adenosine diphosphate (ADP) to adenosine triphosphate (ATP). There is no specific solution, toxic agent, or antagonist for acute Chlorfenapyr poisoning. In recent years, the incidence rate of chlorfenapyr poisoning in China has been on the rise year by year, with a high case fatality rate and no corresponding effective treatment. People have insufficient understanding of acute acaricide poisoning and lack effective treatment methods. At present, there is no corresponding guideline or consensus in China for the treatment of acute chlorfenapyr poisoning. In order to improve the success rate of treatment for acute chlorfenapyr poisoning, this recommendation is proposed to guide clinical practice. |
